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模拟移动床技术在天然产物分离制备中的应用
引用本文:王尉,赵利新,林 楠,徐双双.模拟移动床技术在天然产物分离制备中的应用[J].食品安全质量检测技术,2016,7(11):4346-4351.
作者姓名:王尉  赵利新  林 楠  徐双双
作者单位:北京市理化分析测试中心,北京翔悦环宇科技发展有限公司
摘    要:随着模拟移动床色谱技术(simulated moving bed,SMB)的快速发展,该技术在天然产物活性成分的提取与纯化中的应用日益广泛。本文简述了SMB技术的发展和在天然产物分离中的应用现状,并重点介绍了SMB技术在黄酮类、多酚类、氨基酸以及肽类和糖类分离制备中的应用。与传统的制备色谱技术相比,SMB采用连续操作手段,具有易于自动化操作、制备效率高、制备量大等特点,在天然产物分离制备中具有良好的发展前景。

关 键 词:模拟移动床  黄酮类  多酚类  氨基酸  肽类  糖类  天然产物  分离
收稿时间:2016/9/28 0:00:00
修稿时间:2016/11/24 0:00:00

Application of simulated moving bed technology in separation and preparation of natural products
WANG Wei,ZHAO Li-Xin,LIN Nan and XU Shuang-Shuang.Application of simulated moving bed technology in separation and preparation of natural products[J].Food Safety and Quality Detection Technology,2016,7(11):4346-4351.
Authors:WANG Wei  ZHAO Li-Xin  LIN Nan and XU Shuang-Shuang
Affiliation:Beijing Centre for Physical and Chemical Analysis,Beijing Xiang Yue Huan Yu Science and Technology Development Co,Ltd
Abstract:With the rapid development of simulated moving bed technology (SMB), SMB is increasingly applied to extract and purification of natural products. The development and application of SMB in separation and preparation of natural products is reviewed in this paper. The major applications in flavonoids, polyphenols, amino acid, peptide, saccharides are also reviewed. The SMB is an advanced separation-technology of chromatography compared with traditional technology of chromatography. It has good prospects in separation and preparation of natural products with auto-control, high efficiency and great yield.
Keywords:Simulated  moving bed  Flavonoids  Polyphenols  Amino  acid  Peptide  Saccharides  Natural Products  Sparation
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