IPP-rich milk protein hydrolysate lowers blood pressure in subjects with stage 1 hypertension,a randomized controlled trial |
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| Authors: | Esther Boelsma Joris Kloek |
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| Affiliation: | 1.TNO Quality of Life,Business unit Biosciences,Zeist,The Netherlands;2.DSM Biotechnology Center,Delft,The Netherlands |
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| Abstract: | Background Milk derived peptides have been identified as potential antihypertensive agents. The primary objective was to investigate the effectiveness of IPP-rich milk protein hydrolysates (MPH) on reducing blood pressure (BP) as well as to investigate safety parameters and tolerability. The secondary objective was to confirm or falsify ACE inhibition as the mechanism underlying BP reductions by measuring plasma renin activity and angiotensin I and II. |
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