| 不同辅料对芍甘颗粒喷干粉吸湿性的影响 |
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| 引用本文： | 张艳立,张艳哲,任凤芝.不同辅料对芍甘颗粒喷干粉吸湿性的影响[J].河北化工,2010(1):58-59. |
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| 作者姓名： | 张艳立 张艳哲 任凤芝 |
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| 作者单位： | 华北制药新药研究开发有限责任公司,河北,石家庄,050015 |
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| 摘 要： | 为合理选择芍甘颗粒防潮性最佳的辅料和生产条件，在25℃，RH为75％的条件下，将喷干粉及喷干粉与几种常用辅料配伍，考察吸湿百分率、临界相对湿度。结果表明，防潮性最佳的辅料为乳糖，配比为喷干粉：乳糖=4：1。
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| 关 键 词： | 芍甘颗粒 喷干粉 辅料 吸湿性 |
Influence of Different Excipients on Hygroscopic Property of Spray-dried Powder in Shaogan Granules |
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| ZHANG Yan-li,ZHANG Yan-zhe,REN Feng-zhi.Influence of Different Excipients on Hygroscopic Property of Spray-dried Powder in Shaogan Granules[J].Hebei Chemical Engineering and Industry,2010(1):58-59. |
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| Authors: | ZHANG Yan-li ZHANG Yan-zhe REN Feng-zhi |
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| Affiliation: | (Drug Discovery of North China Pharmaceutical Company, Shijiazhuang 050015, China) |
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| Abstract: | In order to provide experimenal basis for a better choose of spray-dried Powder of shaogan granules with damp-proofing excipients and producing condition. Under 25℃,75% relative humidity, compatibility spray-dried powder and others excipients, inspecting its moisture absorption percentage, critical relative humidity. Result show that the optimized damp-proofing excipient is latcose. The ingredient ratio of spray-dried powder to excipient is 4 ： 1. |
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| Keywords: | shaogan granules spray-dried powder excipients hygroscopic |
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