微波消解-电感耦合等离子体质谱法测定 保健食品中的9种元素

目的建立微波消解-电感耦合等离子体质谱法检测液体水基、固体粉基、软胶囊基3种基质的保健食品中钠、镁、钾、钙、锰、铁、铜、锌、硒9种元素的分析方法。方法前处理方法采用硝酸-双氧水体系的微波消解法,仪器检测方法采用电感耦合等离子体质谱法。对3种基质的保健食品中9种元素进行同时测定。通过在线加入标准溶液实现对样品的实时校正,内标为~(103)Rh和~(185)Re。结果方法的线性范围宽,跨越两个数量级;9种元素相关系数r均在0.999以上;检出限低;9种元素回收率在82%~120%之间;精密度在7.8%以内。结论本方法准确、灵敏、简便,适合进行液体水基、固体粉基、软胶囊基3种基质的保健食品中钠、镁、钾、钙、锰、铁、铜、锌、硒9种元素的同时测定。

Determination of 9 kinds of elements in health food by microwave digestion-inductively coupled plasma mass spectrometry

Objective To establish a method for simultaneous determination of 9 kinds of elements such as Na, Mg, K, Ca, Mn, Fe, Cu, Zn, and Se, in liquid, solid, and soft capsule types of health food by microwave digestion- inductively coupled plasma mass spectrometry (ICP-MS). Methods Nine kinds of elements in 3 kinds of matrix of health food were firstly decomposed by microwave oven with nitric acid and hydrogen peroxide, and then determined simultaneously by ICP-MS. Samples were corrected by adding internal standard solution on line, with 103Rh and 185Re as internal standard. Results This method showed a wide linearity range, and low detection limit. The recoveries were in the range of 82%~120%, and relative standard deviations were under 7.8%. Conclusion This method is rapid, sensitive and accurate, and suitable for the simultaneous determination of Na, Mg, K, Ca, Mn, Fe, Cu, Zn, and Se in 3 kinds of matrix of liquid, solid and soft capsule.