| Preparation and Behaviour of New Materials for Percutaneous Access |
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| 作者姓名： | 王欣宇 |
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| 作者单位： | Biomedical Materials |
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| 基金项目： | FundedbytheNationalNaturalScienceFoundationofChina(No.50472041) |
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| 摘 要： | 1Introduction HAbioceramicsarewidelyusedinclinic,buttheir applicationsaresometimeslimitedowingtolowstrengthof thematerial.Ontheotherhand,theimplantedmaterial ofpercutaneousaccessandbodytissueswillreactmutual lyintheextremelycomplicatedphysiologycircumstan…
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Preparation and Behaviour of New Materials for Percutaneous Access |
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| WANG Xinyu HAN Yingchao CHEN Xiaoming LI Shipu.Preparation and Behaviour of New Materials for Percutaneous Access[J].Journal of Wuhan University of Technology. Materials Science Edition,2005,20(Z1). |
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| Authors: | WANG Xinyu HAN Yingchao CHEN Xiaoming LI Shipu |
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| Abstract: | The reinforcing effects on hydroxyapatite (abbreviated HA) of phosphate glass additives were researched. The samples of reinforced HA (abbreviated RHA) and control material were prepared and then percutaneously implanted in the skin of experiment animal. The histomorphology of the part skin tissue were observed. By a biomimetic process,the method and conditions of forming HA coating on the surface of medical silicon rubber (abbreviated MSR) were studied. The results illustrate that the phosphate glass additives have obvious reinforcing effects on HA. In the percutaneous implantation test, neither clear infiltration of inflammatory cells nor marked downgrowth of epidermis was observed for the part tissue surrounded RHA. The surface modification of MSR for percutaneous access could be attained by biomimetic synthesis of HA coating. |
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| Keywords: | percutaneous access hydroxyapatite reinforcement histocompatibility silicon rubber surface modification |
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