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Assessing Oxazole Bioisosteres as Mutasynthons on the Rhizoxin Assembly Line
Authors:Björn Kusebauch  Nicole Brendel  Heike Kirchner  Dr. Hans‐Martin Dahse  Prof. Dr. Christian Hertweck
Affiliation:1. Department of Biomolecular Chemistry, Hans Kn?ll Institute, Leibniz Institute for Natural Product Research and Infection Biology, Beutenbergstrasse 11a, 07745 Jena (Germany);2. Department of Infection Biology, Hans Kn?ll Institute, Leibniz Institute for Natural Product Research and Infection Biology, Beutenbergstrasse 11a, 07745 Jena (Germany);3. Natural Product Chemistry, Friedrich Schiller University, Jena (Germany)
Abstract:
Keywords:antitumor agents  Burkholderia rhizoxinica  mutasynthesis  PKS–  NRPS  polyketides
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