光镊在生物细胞及生物大分子中的应用研究

利用光镊技术研究生物微粒是目前生物领域的一个研究热点,介绍了光镊基本装置及在生物大分子中力的一般标定法,同时系统地归纳了光镊技术在生物细胞和生物大分子上的理论和实验研究成果.主要有细胞的操控、细胞的应变能力和细胞膜弹性方面的实验研究成果;对于生物大分子中的DNA,RNA等方面的实验研究;最后介绍了光镊结合其他技术在生物...

Application of optical tweezers in biological cell and biopolymer

The study of biological particle in optical tweezers has become a research hotspot in biology territory.In this paper,the basic device of optical tweezers and the standardization of force in biopolymers are simply introduced.Meanwhile,the experimental and theoretical results of optical tweezers in biological cell and biopolymers are reviewed.There are many results in experiment,we mainly introduce the manipulation of cells,the stress response of cells and the elasticity of cellularity,respectively.For biological molecules,the aspects of DNA/RNA and so on are given in this paper.In the end,the application of the combination of optical tweezers and other technologies in biology are present.