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Mechanism of alcohol action on gastric secretion
Authors:Vasilevskaia L S  Skurikhin I M  Guliev R R
Abstract:In chronic experiment on dogs (3 dogs with Pavlov's miniature stomach, 3 dogs with Heidenhain's miniature stomach) the mechanism of action of alcohol (8%-150 ml) on gastric secretion was clarified. For this purpose the new inhibitor of gastric secretion--glycopeptide was utilized, which action was preset in laboratory of G.K. Shlygin. Was shown, that in effect of alcohol on gastric secretion take place the complicated mechanism including as a nervous regulation (vagus nerves), and humoral: participation of gastrin and histamine in secretory effect of a stomach, and also immediate effect of ethanol on acid glands.
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