| N-氨基哌啶盐酸盐的合成 |
| |
| 引用本文： | 冯润良,宋智梅. N-氨基哌啶盐酸盐的合成[J]. 化学试剂, 2009, 31(3) |
| |
| 作者姓名： | 冯润良 宋智梅 |
| |
| 作者单位： | 济南大学,化学化工学院,山东,济南,250022;济南大学,化学化工学院,山东,济南,250022 |
| |
| 基金项目： | 济南大学博士启动基金 |
| |
| 摘 要： | 以哌啶为起始原料,经N-亚硝化、还原以及成盐等合成操作制备标题化合物,总收率66.5%.该合成路线操作简单、收率高,所选试剂价格适中,适合进行工业化生产.
|
| 关 键 词： | N-氨基哌啶盐酸盐 合成 利莫那班 |
Preparation of N-amino piperidine hydrochloride |
| |
| FENG Run-liang,SONG Zhi-mei. Preparation of N-amino piperidine hydrochloride[J]. Chemical Reagents, 2009, 31(3) |
| |
| Authors: | FENG Run-liang SONG Zhi-mei |
| |
| Affiliation: | School of Chemistry and Chemical Engineering;University of Jinan;Jinan 250022;China |
| |
| Abstract: | The title compound was obtained from N-nitrosoamination of piperidine and reduction of nitroso group followed by salt-forming of hydrochloride.N-amino piperidine was obtained at 66.5% yield.The results showed that the synthetic process was simple with high product yield.The synthetic route,which required inexpensive raw materials,was suitable for manufacture in commercial scale. |
| |
| Keywords: | N-amino piperidine hydrochloride synthesis rimonabant |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
