UV/H_2O_2降解水溶液中抗癫痫药物苯巴比妥

采用UV/H2O2法对水溶液中的抗癫痫药物苯巴比妥(PBB)进行降解处理。研究发现:PBB的光解率随H2O2量的增加而增加,随PBB初始浓度的增加而降低。在UV/H2O2体系下PBB紫外光解的最佳p H为10.9。Cl-的存在会降低PBB的光解率,低浓度HCO-3的存在会增加PBB的光解率,高浓度的HCO-3的存在会抑制PBB的光解率。采用离子色谱和LC-MS-MS对PBB光解后的主要产物进行分析,提出了PBB可能的紫外光降解途径。结果表明:UV/H2O2法是去除水溶液中PBB的一种十分有效的方法。

Photodegradation of antiepileptic drug phenobarbital in aqueous solution by UV/H2O2

The paper used UV/H₂O₂ method to remove antiepileptic drug phenobarbital in aqueous solution. The degradation rate of phenobarbital increases with the enhance of H₂O₂ dosage . The photodegradation speed of phenobarbital decreased with the increase of phenobarbital initial concentration.The optimal pH value for Phenobarbital photodegradation in UV/H₂O₂ system is 10.9. The existence of Cl^- can decrease degradation rate of Phenobarbital. The existence of low concentration of HCO^-₃ can increase phenobarbital degradation rate,while the high concentration of HCO^-₃ can decrease phenobarbital degradation rate .The paper applied the ion chromatography and LC-MS-MS to analyze the main product after degradation rate of Phenobarbital,and propose the possible degradation way of ultraviolet of PBB.were detected and identified during phenobarbital photooxidation process. UV/H₂O₂ has been proven to be an effective method for removal of phenobarbital from aqueous solution.