Polymeric nanostructured materials for biomedical applications |
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Affiliation: | 1. School of Chemistry and Chemical Engineering, Central South University, Lushan South Road 932, Changsha Hunan 410083, China;2. ShenZhen Research Institute, Central South University, Yuanna Road 607, Shenzhen Guangdong 518057, China;1. Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, PR China;2. University of Chinese Academy of Sciences, Beijing 100039, PR China;1. Department of Mechanical Engineering, University College London, London, United Kingdom;2. UNC/NCSU Joint Department of Biomedical Engineering, Raleigh, NC, United States |
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Abstract: | Polymeric nanostructured materials (PNMs), which are polymeric materials in nanoscale or polymer composites containing nanomaterials, have become increasingly useful for biomedical applications. In specific, advances in polymer-related nanoscience and nanotechnology have brought a revolutionary change to produce new biomaterials with tailored properties and functionalities for targeted biomedical applications. These materials, including micelles, polymersomes, nanoparticles, nanocapsules, nanogels, nanofibers, dendrimers and nanocomposites, have been widely used in drug delivery, gene therapy, bioimage, tissue engineering and regenerative medicine. This review presents a comprehensive overview on the various types of PNMs, their fabrication methods and biomedical applications, as well as the challenges in research and development of future PNMs. |
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Keywords: | Polymer Nanostructure Biomaterials Nanocarriers Biomedical applications |
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