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Green synthesis of multifunctional carbon dots for anti-cancer and anti-fungal applications
Authors:Shaojing Zhao  Li Huang  Yong Xie  Bin Wang  Feng Wang  Minhuan Lan
Abstract:Carbon dots (CDs) have become popular nanomaterials in biomedical and agricultural fields.Herein we synthesized multifunctional CDs which showed anti-cancer and anti-fungal activities.The low cytotoxi-city,stable fluorescence and high photothermal conversion efficiency enable the CDs with imaging-guided photothermal therapy.The CDs also exhibited intrinsic anti-fungal activity even at a low concen-tration,i.e.,40 mg·L-1 of CDs induced 20% mortality in cucumber downy mildew.Moreover,the large π-conjugated nanostructure and the richness of amino and hydroxyl groups make them a powerful delivery platform for flumorph (a fungicide) with a high loading efficiency of 47.18%.Meanwhile,the heat con-verted from the light can accelerate the release of flumorph from CDs,and thus efficiently kill fungus.
Keywords:Carbon dots  Photothermal therapy  Anti-fungus  Delivery  Pesticide
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