Synthesis of a series of sulfinic acid analogs of GABA and evaluation of their GABAB receptor affinities |
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| Authors: | NI Carruthers JM Spitler SC Wong DJ Blythin X Chen HJ Shue HS She JF Lee C Rizzo PC Ting RE West |
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| Affiliation: | Department of Chemical Research, Schering-Plough Research Institute, Kenilworth, NJ 07033, USA. |
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| Abstract: | A series of gamma-aminobutyric acid (GABA) 1 analogs was prepared in which the carboxylic acid group of GABA was replaced with a sulfinic acid group and their affinity for the GABAB receptor investigated. |
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