| 含芳硫(芳氧)乙酸的新三唑类化合物的合成与生物活性研究 |
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| 引用本文： | 陈风友,刘淑玲,杨双花,朱琪. 含芳硫(芳氧)乙酸的新三唑类化合物的合成与生物活性研究[J]. 山东化工, 2005, 34(3): 15-17 |
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| 作者姓名： | 陈风友 刘淑玲 杨双花 朱琪 |
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| 作者单位： | 青岛碱业股份有限公司双收农药分公司,山东,青岛,266300;青岛科技大学,化学与分子工程学院,山东,青岛,266042 |
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| 摘 要： | 以苯(硫)酚、氯乙酸、N-溴代丁二酰亚胺和1-H-1,2,4-三氮唑为主要原料,通过O-烷基化、酯化、溴化、N-烷基化及水解反应合成了五种新型三唑类化合物。其结构经IR、1HNMR、EA和MS确证。初步生物活性测试表明,此类化合物有一定的杀菌活性。
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| 关 键 词： | 三氮唑衍生物 合成 芳硫(氧)乙酸 生物活性 |
| 文章编号： | 1008-021X(2005)02-0015-03 |
| 修稿时间： | 2004-11-19 |
Study on Synthesis and Structure of Novel Triazole Compounds Containing Arylsulphur or Aryloxygen Acetic Acid |
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| CHEN Feng-you,LIU Shu-ling,YANG Shuang-hua,ZHU qi. Study on Synthesis and Structure of Novel Triazole Compounds Containing Arylsulphur or Aryloxygen Acetic Acid[J]. Shandong Chemical Industry, 2005, 34(3): 15-17 |
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| Authors: | CHEN Feng-you LIU Shu-ling YANG Shuang-hua ZHU qi |
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| Affiliation: | CHEN Feng-you~1,LIU Shu-ling~1,YANG Shuang-hua~2,ZHU qi~2 |
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| Abstract: | Five novel triazole compounds were synthesized through O-alkylation, esterification, bromination, N-alkylation and hydrolization reaction using phenol or benzenthiol 2-chloroacetic acid N-bromosuccinimide and 1H-1,2,4-triazole. Their structures were confirmed by IR,()~1H NMR, EA and MS. Preliminary biological test shows that the synthesized compounds exhibits some fungicidal activities. |
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| Keywords: | 1H-1 2 4-triazole derivative synthsis arylsulphur or aryloxygen actic acid bioactivity |
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