Phytotoxic Iridoid Glucosides from the Roots of Verbascum thapsus |
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Authors: | F Pardo F Perich R Torres F Delle Monache |
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Affiliation: | (1) Departamento de Ciencias Químicas, Universidad de La Frontera, Casilla 54-D, Temuco, Chile;(2) Facultad de Química y Biología, Departamento de Ciencias Químicas, Universidad de Santiago de Chile, Casilla 307, Correo 2, Santiago, Chile;(3) Centro Chimica Recettori, CNR, Largo Francesco Vito 1, 00168 Roma, Italy |
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Abstract: | The iridoid glucosides lateroside 1, harpagoside 2, ajugol 3, and aucubin 4 were isolated from an ethanolic extract of the roots of the weed Verbascum thapsus that exhibits antigermination activity on seeds of barley (Hordeum vulgare). Bioassays indicated that at 3 mM concentration, compounds 1, 2, and 4 showed moderate inhibition of seed germination. These compounds also reduced root length when they were assayed on pregerminated seeds at 1 mM to 0.001 mM concentration range. Of all compounds tested, aucubin 4 was the most active against root elongation. Compound 3 showed no activity in the bioassays. |
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Keywords: | Verbascum thapsus weeds iridoid glycosides phytotoxicity barley Hordeum vulgare germination root inhibition |
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