Sorption of Mo(VI) on zirconium molybdosilicate gel and potential application as a 99Mo/99m Tc generator

Sorption of Mo(VI) from aqueous nitrate solutions onto zirconium molybdosilicate (ZrMoSi) gel was studied using ⁹⁹Mo radiotracer. The acid–base titration curve showed that the prepared ZrMoSi gel was an amphoteric material with the point of zero charge (PZC) at pH 2.5. The highest distribution coefficient (600 mL g^–1) of ⁹⁹Mo(VI) on ZrMoSi from nitrate media was achieved at pH 2.1. The sorption kinetics of ⁹⁹Mo(VI) onto ZrMoSi obeyed the pseudo-second-order model. The breakthrough sorption capacity of ZrMoSi gel was found to be 4.25 × 10^–2 [mmol Mo(VI)] g^–1. The prepared ⁹⁹Mo/^99mTc chromatographic column generator showed a good performance: The ^99mTc elution yield was 87.7%, pH of the eluate ranged from 5.6 to 7.2, and the radionuclidic purity of the eluted ^99mTc was >99.99% with a radiochemical purity of 98.31% (as ^99mTcO₄^–).