一种新型白蒿精油空气清新剂的研制

研制一种新型白蒿精油杀菌空气清新剂。传统水蒸气蒸馏法提取白蒿精油,微孔稀释法考察其抑菌活性。为了提高精油的利用率,采用β-环糊精(β-CD)微胶囊技术对其进行包合,从而研制成新型喷雾空气清新剂,并在流通的病房考察空气清新剂的消毒效果。结果表明,白蒿精油具有广谱抗菌效果,对实验所用的致病菌有较强的抑制和灭活作用。对大肠埃希氏菌和白假丝酵母菌的MIC可达7.8μL/mL,MBC值范围为7.80～60.50μL/mL。白蒿精油空气清新剂消毒效果显著的高于对照,其杀菌率为85.63%。白蒿精油空气清新剂具有较强的空间灭菌作用,是一种有效的新型空气消毒剂。

Study on formula of a new type of air disinfectant made from essential oil of Artemisia anethoides Mattf.

The formula of a new type of air disinfectant made from essential oil(EO) of Artemisia anethoides Mattf.was studied.The essential oil was extracted by traditional steam distillation method and microplate bioassay was used to evaluate the antibacterial activities of essential oil.In order to improve the utilization of essential oil,the inclusion complex between β-CD-EO was prepared by blending method and a new spray air pure and fresh agent was abtained,and the air sanitized effect of the air refreshing agents was observed in open ward.In the case of antimicrobial activity,the results possessed broad and remarkable antimicrobial activity against the microorganisms tested containing 10 bacteria,the minimal inhibitory concentration(MIC) value for bacteria was 7.8 μL/mL and the minimal bactericidal concentration(MBC) was from 7.80~60.50 μL/mL.The pencentage of air-disinfectant effects of air refreshing agents was 85.63%,significantly higher than the control(84 disinfection).The air refreshing agents has a strong spacious sterilizing effect and is an effective and new type vaporizer for air sterilizing.