| 均匀设计优化白花蛇舌草中对香豆酸的提取工艺 |
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| 引用本文： | 刘静,郭森辉,李国强,钟惠民. 均匀设计优化白花蛇舌草中对香豆酸的提取工艺[J]. 青岛科技大学学报(自然科学版), 2007, 28(5): 394-396 |
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| 作者姓名： | 刘静 郭森辉 李国强 钟惠民 |
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| 作者单位： | 青岛科技大学,化学与分子工程学院,山东,青岛,266042;中国海洋大学,海洋药物与食品研究所,山东,青岛,266003 |
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| 基金项目： | 国家高技术研究发展计划(863计划);山东省青岛市自然科学基金 |
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| 摘 要： | 采用均匀设计优化白花蛇舌草中对香豆酸的提取工艺。以对香豆酸含量、干浸膏得率为指标,考察药材的提取溶剂、溶媒量、提取温度、提取时间等因素对提取工艺的影响。优化工艺:水为提取溶剂,料液质量比1∶100,提取温度100℃,提取时间4 h。提取工艺可靠、简便。
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| 关 键 词： | 白花蛇舌草 均匀设计 对香豆酸 高效液相色谱法 提取工艺 |
| 文章编号： | 1672-6987（2007）05-0394-03 |
| 收稿时间： | 2006-11-10 |
| 修稿时间： | 2006-11-10 |
Optimization for Extraction Process of p-Coumaric Acid from Hedyotis Diffusa Willd. Using Uniform Design |
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| LIU Jing,GUO Sen-hui,LI Guo-qiang,ZHONG Hui-min. Optimization for Extraction Process of p-Coumaric Acid from Hedyotis Diffusa Willd. Using Uniform Design[J]. Journal of Qingdao University of Science and Technology:Natutral Science Edition, 2007, 28(5): 394-396 |
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| Authors: | LIU Jing GUO Sen-hui LI Guo-qiang ZHONG Hui-min |
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| Affiliation: | 1.College of Chemistry and Molecular Engineering;Qingdao University of Science and Technology;Qingdao 266042;China;2.Institute of Marine Drugs and Food;Ocean University of China;Qingdao 266003;China |
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| Abstract: | The extraction process of p-coumaric acid from hedyotis diffusa willd.was optimized by uniform design.The effects of kinds of extracting agent,amount of extracting agent,temperature and time on extraction results were examined.The obtained optimum extraction conditions were using water as extracting agent,w(hedyotis diffusa willd)∶w(water) =1∶100,extraction temperature 100℃,and extraction time 4 h.The results showed that this method is reliable and simple for extraction of p-coumaric acid from hedyotis diffusa willd. |
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| Keywords: | hedyotis diffusa willd. uniform design p-coumaric acid HPLC extraction process |
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