| Fabrication, in vitro Degradation and Cytotoxic Assay of Different Crystalline Phases Calcium Polyphosphate |
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| 引用本文： | QIU Kai WANG Fengming WAN Changxiu HU Tao TANG Changwei. Fabrication, in vitro Degradation and Cytotoxic Assay of Different Crystalline Phases Calcium Polyphosphate[J]. 武汉理工大学学报(材料科学英文版), 2005, 20(B12): 111-113 |
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| 作者姓名： | QIU Kai WANG Fengming WAN Changxiu HU Tao TANG Changwei |
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| 作者单位： | [1]Department of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China [2]Department of Operative Dentistry and Endodontics , West China College of Stomatology, Chengdu 610041, China |
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| 基金项目： | Funded by the National Natural Science Foundation of China （50472091） |
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| 摘 要： | Fabrication, in vitro degradation and cytotoxic assay of different crystalline phases calcium polyphosphate（CPP） were reported. The CPP ceramics were fabricated by crystallizing the amorptous frits, and sintered at 550℃ ,875℃, 1000℃ for 1 h to obtain the 7-CPP, β-CPP and α-CPP respectively. The efffects of the different crystalline phases on their weight loss and released PO4^3- were investigated during the degradation. And the surface change was observed by the SEM, The osteoblastic ROS17/2.8 cell line was used to estimate the cytotoxicity of CPP. The effects of CPP on cells ＇ proliferation were evaluated by using MTT assay. The experimental restdts showed that γ-CPP, β-CPP and α-CPP did not exert cytotoxic effect on the cells. In addition, the proliferation of the growth of ROS17/2.8 cells on β-CPP was optimal.
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| 关 键 词： | 聚磷酸钙 体外降解 细胞毒性测定 结晶相 生物材料 |
| 收稿时间： | 2005-05-10 |
| 修稿时间： | 2005-09-05 |
Fabrication, in vitro Degradation and Cytotoxic Assay of Different Crystalline Phases Calcium Polyphosphate |
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| QIU;Kai;WANG;Fengming;WAN;Changxiu;HU;Tao;TANG;Changwei. Fabrication, in vitro Degradation and Cytotoxic Assay of Different Crystalline Phases Calcium Polyphosphate[J]. Journal of Wuhan University of Technology. Materials Science Edition, 2005, 20(B12): 111-113 |
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| Authors: | QIU Kai WANG Fengming WAN Changxiu HU Tao TANG Changwei |
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| Abstract: | |
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| Keywords: | calcium polyphosphate degradation cytotoxicity MTT |
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