| 纳豆粉对小鼠免疫调节作用的试验研究 |
| |
| 引用本文： | 彭亮,王彦武,傅伟忠,何励,覃辉艳,姚思宇. 纳豆粉对小鼠免疫调节作用的试验研究[J]. 中国食品卫生杂志, 2014, 26(4): 336-339 |
| |
| 作者姓名： | 彭亮 王彦武 傅伟忠 何励 覃辉艳 姚思宇 |
| |
| 作者单位： | 广西壮族自治区疾病预防控制中心,广西 南宁 530028;广西壮族自治区疾病预防控制中心,广西 南宁 530028;广西壮族自治区疾病预防控制中心,广西 南宁 530028;广西壮族自治区疾病预防控制中心,广西 南宁 530028;广西壮族自治区疾病预防控制中心,广西 南宁 530028;广西壮族自治区疾病预防控制中心,广西 南宁 530028 |
| |
| 基金项目： | 国家自然科学基金(81273108)；首都卫生发展科研专项(首发2011-1013-03)；北京市卫生系统高层次卫生技术人才培养项目(2011)；北京市优秀人才培养项目(2013) |
| |
| 摘 要： | 探讨纳豆粉对小鼠的免疫调节作用。方法 以不同剂量的纳豆粉连续经口给予小鼠30 d,然后通过细胞免疫、体液免疫、吞噬系统功能、自然杀伤细胞活性4个方面的试验结果评价纳豆粉对小鼠免疫系统的作用。结果 纳豆粉能够增强小鼠的脾淋巴细胞增殖、转化作用,提高小鼠的迟发型变态反应程度,促进小鼠的抗体生成细胞增殖,提高小鼠的血清溶血素水平,增强小鼠的单核-巨噬细胞碳廓清能力和腹腔巨噬细胞吞噬能力,对自然杀伤细胞活性无明显影响。结论 纳豆粉可提高小鼠的免疫力。
|
| 关 键 词： | 纳豆 免疫调节 小鼠 毒理学试验 |
| 收稿时间： | 2013-09-10 |
Experimental study on effect of natto powder on immunological function of mice |
| |
| PENG Liang,WANG Yan-wu,FU Wei-zhong,HE Li,QIN Hui-yan and YAO Si-yu. Experimental study on effect of natto powder on immunological function of mice[J]. Chinese Journal of Food Hygiene, 2014, 26(4): 336-339 |
| |
| Authors: | PENG Liang WANG Yan-wu FU Wei-zhong HE Li QIN Hui-yan YAO Si-yu |
| |
| Affiliation: | Guangxi Autonomous Regional Center for Disease Control and Prevention,Guangxi Nanning 530028,China;Guangxi Autonomous Regional Center for Disease Control and Prevention,Guangxi Nanning 530028,China;Guangxi Autonomous Regional Center for Disease Control and Prevention,Guangxi Nanning 530028,China;Guangxi Autonomous Regional Center for Disease Control and Prevention,Guangxi Nanning 530028,China;Guangxi Autonomous Regional Center for Disease Control and Prevention,Guangxi Nanning 530028,China;Guangxi Autonomous Regional Center for Disease Control and Prevention,Guangxi Nanning 530028,China |
| |
| Abstract: | To explore the effect of natto powder on the immunological function in mice.MethodsNatto powder were consecutively orally administered to mice with different dosage for 30 d. Humoral immunity, cellular immunity, phagocytic system function and activity of natural killer cell were used to access the effect of natto powder on immunological function. ResultsNatto powder could stimulate proliferation and transformation of mice''s spleen lymphocytes, promote delayed hypersensitivity, increase the quantity of antibody producing cells, enhance the level of serum hemolysin, accelerate the carbon clearance and intensify the peritoneal macrophage, and had no significant effect on activity of natural killer cell in mice.ConclusionIt suggested that natto powder could enhance the immune function in mice. |
| |
| Keywords: | |
|
| 点击此处可从《中国食品卫生杂志》浏览原始摘要信息 |
|
点击此处可从《中国食品卫生杂志》下载全文 |
|
