| 灵芝转化小球藻发酵液粗多糖对荷瘤小鼠免疫功能的影响 |
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| 引用本文： | 杨从发,丁重阳,章克昌.灵芝转化小球藻发酵液粗多糖对荷瘤小鼠免疫功能的影响[J].中国酿造,2009(6). |
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| 作者姓名： | 杨从发 丁重阳 章克昌 |
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| 作者单位： | 1. 江南大学,工业生物技术教育部重点实验室,江苏,无锡,214122;淮海工学院,海洋学院,江苏,连云港,222000
2. 江南大学,工业生物技术教育部重点实验室,江苏,无锡,214122 |
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| 摘 要： | 在灵芝基础培养基中添加蛋白核小球藻粉，灵芝能对小球藻细胞进行生物破壁，同时进行生物转化。提取转化多糖，与基础培养基所产多糖进行比较，研究对荷瘤动物免疫功能的影响。结果表明，产生的转化多糖能显著提高荷瘤小鼠白细胞的数量、脾细胞增殖能力和单核巨噬细胞吞噬能力等免疫学功能功能，对其他免疫调节功能也有一定的提高作用，从而显著地提高了抑瘤效果。
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| 关 键 词： | 灵芝 蛋白核小球藻 多糖 免疫功能 抗肿瘤 |
Effects of polysaccharides from ferment liquid of bioconverted Chlorella pyrenoidosa by Ganoderma lucidum on immunological function of tumor-beard mice |
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| YANG Congfa,DING Zhongyang,ZHANG Kechang.Effects of polysaccharides from ferment liquid of bioconverted Chlorella pyrenoidosa by Ganoderma lucidum on immunological function of tumor-beard mice[J].China Brewing,2009(6). |
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| Authors: | YANG Congfa DING Zhongyang ZHANG Kechang |
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| Abstract: | Ganoderma lucidum could break cell wall of Chlorella pyrenoidosa and produce bioconverted - polysaccharides when C.pyrenoidosa powder was appended in basic medium of G.lucidum.Effects on immunological function of tumor-beard mice were studied though comparing the polysaccharides from bioconverted polysaccharides could significantly increase the number of white blood cell, the proliferation of lymphocytes, and the phagocytic function by macrophages at the optimum dose.Therefore, the anti-tumor effect was enhanced significantly. |
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| Keywords: | Ganoderma lucidum Chlorella pyrenoidosa polysaccharides immunological function anti-tumor |
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