| 一种鉴定蛋白质突变和翻译后修饰的算法 |
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| 引用本文： | 谢靖宇,谢深泉.一种鉴定蛋白质突变和翻译后修饰的算法[J].计算机工程与应用,2007,43(28):61-64. |
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| 作者姓名： | 谢靖宇 谢深泉 |
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| 作者单位： | 湘潭大学 信息工程学院,湖南 湘潭 411105 |
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| 摘 要： | 提出的MSA（Modified Spectral Alignment）算法,改进了SA（Spectral Alignment）算法中D（k）和k-最佳Spectral Alignment的求解方式,并在算法中引入“双端考虑”。实验结果数据表明,MSA算法有效地提高了鉴定含突变或翻译后修饰的蛋白质的能力。
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| 关 键 词： | 蛋白质 翻译后修饰 突变 MSA算法 |
| 文章编号： | 1002-8331（2007）28-0061-04 |
| 修稿时间： | 2007-02 |
Algorithm identifying mutations and post-translational modification of protein |
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| XIE Jing-yu,XIE Shen-quan.Algorithm identifying mutations and post-translational modification of protein[J].Computer Engineering and Applications,2007,43(28):61-64. |
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| Authors: | XIE Jing-yu XIE Shen-quan |
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| Affiliation: | College of Information Engeering,Xiangtan University,Xiangtan,Hunan 411105,China |
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| Abstract: | The algorithm MSA is presented in this paper,which improved the way to compute D(k) and k-optimal Spectral Alignment of SA algorithm and took into account simultaneous analysis of N-terminal and C-terminal ions.The experiment result data shows that efficiently improves the capability of identifying proteins containing mutations or post-translational modifications. |
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| Keywords: | protein Post-translational Modification mutation MSA algorithm |
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