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Severe colitis in mucoviscidosis
Authors:JC Fournet  A Lavergne  M Lémann  C Silly  M Sorin  R Modigliani  G Lenoir  N Brousse
Affiliation:Service d'Anatomie et de Cytologie Pathologiques, H?pital Necker-Enfants Malades, Paris.
Abstract:We report the association of severe indeterminate colitis with cystic fibrosis in a 21 year old woman, with mild pulmonary involvement, and without digestive or pancreatic symptoms or pancreatic enzyme preparation. Ten cases of inflammatory bowel disease associated with a cystic fibrosis have been reported. Most fit with the diagnostic criteria of Crohn's disease. Although this case was compatible with this diagnosis, we have retained the diagnosis of "severe indeterminate colitis" because of the lack of specific histological features of Crohn's disease. The association between inflammatory bowel disease and cystic fibrosis is probably not fortuitous, although the pathophysiological link between the two diseases is unknown.
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