硝酸盐、亚硝酸盐和烟碱对卷烟主流烟气中烟草特有N-亚硝胺的影响

研究了卷烟主流烟气中烟草特有N亚硝胺及其前体的相互关系,通过在卷烟烟支中分别加入硝酸盐、亚硝酸盐、烟碱,采用标准方法对烟气总粒相物进行捕集,捕集后的样品进行前处理,采用内标法对烟草特有N亚硝胺(TSNAs)进行气相热能分析仪(GCTEA)定量分析,分别研究了4种烟草特有N亚硝胺(NNN、NAT、NAB、NNK)及其总量与硝酸盐、亚硝酸盐和烟碱的相互关系。研究结果表明:硝酸盐、亚硝酸盐、烟碱均是烟草特有N亚硝胺的重要前体物质,随着这些前体物质含量的增加,卷烟主流烟气中的烟草特有N亚硝胺含量也增加,表现出显著的相关关系。 

Influence of nitrate, nitrite and nicotine on tobacco specific N-nitrosamines in mainstream smoke

In this paper, the relationships between tobacco-specific N-nitrosamines in mainstream smoke and their precursors were studied. The nitrate, nitrite, nicotine were added respectively into the Jiadele blend cigarettes, the total particular matter was collected according to the standard method. The treated samples were analyzed quantitatively by GC-TEA according to the internal standard method. The relationships between NNN, NAT, NAB, NNK, total level of tobacco-specific N-nitrosamines and nitrate, nitrite, nicotine were estimated. The results showed that the nitrate, nitrite and nicotine were the important precursors of the tobacco-specific nitrosamines. With the amounts of the added precursors enhanced, the level of tobacco-specific nitrosamines increased. There were significant relationships between these precursors and tobacco-specific N-nitrosamines.