| 聚芳醚酮的表面修饰及其在生物医用领域的应用 |
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| 引用本文： | 孙辉,孙杰,徐英凯,许国志.聚芳醚酮的表面修饰及其在生物医用领域的应用[J].中国塑料,2010,24(1):6-10. |
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| 作者姓名： | 孙辉 孙杰 徐英凯 许国志 |
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| 作者单位： | 北京工商大学 轻工业塑料加工应用研究所 |
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| 基金项目： | 教育部留学回国人员科研启动基金项目; 北京市科委科技面上项目基金项目; 科技部科研院所技术开发研究专项基金(NCSTE-2007-JKZX-016) |
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| 摘 要： | 综述了特种工程塑料聚芳醚酮的表面修饰方法及其在生物医用领域的应用。重点介绍了选择性湿化学法和等离子体处理等聚芳醚酮表面改性方法及通过固定细胞外基质的生物功能化途径；最后，介绍了聚芳醚酮及改性聚芳醚酮在细胞培养基体、椎间融合器、关节摩擦面等临床植入体方面的应用进展，并对聚芳醚酮在生物医用领域的发展前景进行了展望。
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| 关 键 词： | 聚芳醚酮 表面修饰 细胞培养 细胞行为 临床应用 植入体 |
| 收稿时间： | 2009-10-28 |
Surface Modification of Poly (aryl ether ketone)s and Their Biomedical Applications |
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| SUN Hui,SUN Jie,XU Yingkai,XU Guozhi.Surface Modification of Poly (aryl ether ketone)s and Their Biomedical Applications[J].China Plastics,2010,24(1):6-10. |
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| Authors: | SUN Hui SUN Jie XU Yingkai XU Guozhi |
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| Affiliation: | SUN Hui1,SUN Jie2,XU Yingkai3,XU Guozhi1(1.Department of Materials Science , Engineering,Beijing Technology , Business University,Beijing 100048,China,2.Liaoyuan Maternity Hospital,Liaoyuan 136200,3.Department of Surgery,University of Pittsburgh,Pittsburgh 15213,U.S.A.) |
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| Abstract: | In this paper,various methods for surface modification of poly(aryl ether ketone)s and their biomedical applications were described.The selective wet chemistry,plasma treatment,and the surface biofucntionalization via immobilization of extracellular matrix,e.g.fibronectin,were introduced.The application of such polymers as cell-culture substrates,trauma implants,load-bearing joint surface,and spine cages was also discussed.The future development in this area was forecast. |
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| Keywords: | poly(aryl ether ketone) surface modification cell culture cell behavior clinical application implant |
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