| Abstract: | Examined cognitive functions in 11 positive-symptom (mean age 36 yrs), 10 negative-symptom (mean age 33.8 yrs), and 23 mixed-symptom (mean age 31.4 yrs) schizophrenics; 15 bipolar patients (mean age 34.7 yrs); and 12 normal controls (mean age 34.8 yrs) to explore the relation between symptoms and performance. Ss were administered a neuropsychological test battery including the Purdue Pegboard, the Revised Visual Retention Test, and the Block Design subtest of the Wechsler Adult Intelligence Scale—Revised (WAIS—R). Group comparisons revealed generalized deficits in schizophrenics. Positive-symptom schizophrenics scored below normal Ss and negative-symptom Ss on 2 measures tapping verbal memory. Multiple regression analyses revealed that negative symptom ratings were inversely associated with performance on visual-motor tasks, whereas positive symptoms were inversely associated with verbal memory performance. Findings are not consistent with the notion that cognitive deficits are uniquely associated with negative symptoms. Instead, results suggest that there may be specific cognitive correlates of both the positive and negative symptom dimensions. (38 ref) (PsycINFO Database Record (c) 2010 APA, all rights reserved) |
