Tumor necrosis factor and AIDS |
| |
Authors: | N Kobayashi |
| |
Affiliation: | Inserm U229, Laboratoire d'Audiologie Expérimentale, H?pital Pellegrin, Bordeaux, France. |
| |
Abstract: | A guinea pig model with surgically induced endolymphatic hydrops of the inner ear has been developed and studied over the past thirty years. The aim of such studies is to obtain insight into physiological processes associated with endolymphatic hydrops in man and in particular in Menière's disease where endolymphatic hydrops is systematically encountered at post-mortem examination of the temporal bones. The present review attempts to draw together the data pertaining to functional modifications of inner ear function in the animal model. For simplicity the data are categorised under five main titles: electrochemical modifications, electrophysiological modifications, pressure and hydrops, sensitivity to other insults and vestibular dysfunction. One of the most striking observations that can be made is that the data originating from different authors are very variable. There is, however, some evidence suggesting that the evolution of the auditory dysfunction could be considered as consisting of a series of different phases. This kind of information could serve as a basic framework for future research on the animal model. |
| |
Keywords: | Robotics Excavation Control systems Motion Sensors Data collection Decision making |
本文献已被 PubMed 等数据库收录! |
|