混合物联合暴露风险评估方法进展及其对我国构建相关体系借鉴作用

基于人类通过多种途径暴露于多种物质,以及混合物共存可能诱导联合毒性效应的现实,混合物联合暴露风险评估受到国际社会的广泛关注。许多国家依据各自提出的评估指南开展风险评估,其评估结果为科学决策提供依据。本文通过分析国际上混合物联合暴露风险评估模型构建方法和框架,探讨构建我国食品中混合物联合作用风险评估体系和框架。

Advance on risk assessment methods of multiple chemicals combined exposure and its enlightenment to the construction of relevant systems in China

People in the real world are exposed to multiple chemicals via multiple routes and co-exposure to multiple agents may induce joint effects, which draws extensive attention from the international community. Regulations of many countries oblige risk assessors to conduct cumulative risk assessments based on their own guidelines, findings of which provide the basis for scientific decision-making. By analyzing the method and frameworks of international risk assessment models of multiple chemicals, this paper explores the establishment of a risk assessment framework of multiple chemicals combined exposure to in food in China.