| 壳聚糖与葡甘聚糖共混材料的制备及其性能表征 |
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| 引用本文： | 李娜娜,陈寰贝,潘兴华,董会,陈庆华. 壳聚糖与葡甘聚糖共混材料的制备及其性能表征[J]. 昆明理工大学学报(自然科学版), 2009, 34(6): 23-28. DOI: 10.3969/j.issn.1007-855x.2009.06.005 |
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| 作者姓名： | 李娜娜 陈寰贝 潘兴华 董会 陈庆华 |
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| 作者单位： | 1. 昆明理工大学,材料科学与工程学院,云南,昆明,650093
2. 中国人民解放军成都军区昆明总医院干细胞与组织器官工程研究中心,云南,昆明,650032 |
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| 基金项目： | 中国意大利政府合作项目 |
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| 摘 要： | 以葡甘聚糖和壳聚糖为主要原料，采用36％的乙酸溶解壳聚糖，通过共混的方法制备壳聚糖与葡甘聚糖共混膜液，经静置减压脱泡、倒膜、干燥制膜，并用与乙酸等物质量的氢氧化钠对膜进行处理。通过IR、XRD和生物学显微镜对共混膜进行性能表征，同时测定了共混膜的透光率、力学性能、吸水率及水蒸气透过系数。结果表明：共混膜的力学性能和水蒸气透过系数得到改善，葡甘聚糖和壳聚糖之间有强烈的相互作用和良好的相容性，作为一种潜在的皮肤组织工程支架将具有良好的应用前景。
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| 关 键 词： | 葡甘聚糖 壳聚糖 共混膜 组织工程 |
Preparation and Characterization of Chitosan and Konjac Glucomannan Blend Films |
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| LI Na-na,CHEN Huan-bei,PAN Xing-hua,DONG Hui,CHEN Qing-hua. Preparation and Characterization of Chitosan and Konjac Glucomannan Blend Films[J]. Journal of Kunming University of Science and Technology(Natural Science Edition), 2009, 34(6): 23-28. DOI: 10.3969/j.issn.1007-855x.2009.06.005 |
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| Authors: | LI Na-na CHEN Huan-bei PAN Xing-hua DONG Hui CHEN Qing-hua |
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| Affiliation: | LI Na-na,CHEN Huan-bei,PAN Xing-hua,DONG Hui,CHEN Qing-hua(1. Faculty of Metallurgical and Energy Engineering, Kunming University of Science and Technology, Kunming 650093, China;2. People＇s Liberation Army General Hospital of Chengdu Military Region Kunming Stem Cells Tissues and Organs with the Engineering Research Center,Kunming 650032,China) |
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| Abstract: | Konjac glucomannan and chitosan blend films were prepared by solvent - casting method. Chitosan was dissolved with 36% acetic acid. The liquids were blended to form a sol. The sol were poured into the disks. The disks were put into the deeompresssion condition to dry into films. The acetic aeidin the films were neutralization via sodium hydroxide solution. The optical transmittance, mechanical properties, water absorptivity, water vapor permeability coefficient were investigated. The film was characterized via FT-IR and XRD. The results showed that the mechanical property and water vapor permeability coefficient of the blend film were improved ; There are strong interactions and good compatibility between chitosan and konjac glucomannan. It reveals that the blend film has a good prospect as potential skin scaffolds in tissue engineering. |
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| Keywords: | Konjac glueomannan Chitosan blend film tissue engineering |
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