Progress toward the production of long-chain polyunsaturated fatty acids in transgenic plants |
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Authors: | Email author" target="_blank">Johnathan?A?NapierEmail author Olga?Sayanova Baoxiu?Qi Colin?M?Lazarus |
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Affiliation: | (1) School of Biological Sciences, University of Bristol, BS8 1UG Bristol, UK;(2) Department of Biology and Biochemistry, University of Bath, BA2 7AY Bath, UK;(3) Crop Performance and Improvement Division, Rothamsted Research, AL5 2JQ Herts, Harpenden, UK |
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Abstract: | Long-chain PUFA such as eicosapentaenoic and docosahexaenoic acids are prevalent in fish oils, and these compounds have been
demonstrated to play important roles in human health and nutrition. In particular, these n−3/omega-3 long-chain PUFA provide
protection from cardiovascular disease and a collection of symptoms (termed metabolic syndrome) associated with progression
toward type 2 diabetes and obesity. Within Western populations, a large increase in the occurrence of these conditions represents
a major public health concern. Unfortunately, both marine fish stocks and (consequentially) consumption of fish oils are in
steep decline, limiting the protective role of long-chain PUFA in human health. One alternative approach to the provision
of these health-beneficial FA is via their synthesis in transgenic plants. This review will describe recent advances in the production of transgenic plant oils
nutritionally enhanced to produce long-chain PUFA. |
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