Insulin concentration in plasma from the femoral, hepatic and pancreatico-duodenal veins of dogs under standard conditions and in corisone glucose tolerance tests

In comparing the results of glucose tolerance tests conducted against the background of cortisone action and without it the former one proved to have advantages over the latter one in studying the incretory function of the pancreas. A biphasic character of insulin secretion in glucose loading was revealed with the aid of this test. Secretion of insulin by the pancreas was better reflected by the dynamics of insulin content in the blood of the pancreatic-duodenal vein that by the dynamics of its content in the blood of the peripheral veins.