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Study of new sheep bone and Zn/Ca ratio around TiAlV screw: PIXE-RBS analysis |
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| Authors: | G. Guibert F. Munnik B. Von Rechenberg D. Laub F. Ducret S. Mikhailov |
| Affiliation: | a Haute Ecole Arc Ingénierie, IMA-Arc-NEODE, 17 Eplatures-Grise, CH-2300 La Chaux-de-Fonds, Switzerland b MSRU, Universität Zürich, CH-8057 Zürich, Switzerland c EPFL-CIME, CH-1015 Lausanne, Switzerland d DePuy ACE, CH-2400 Le Locle, Switzerland e Institute of Cell Biology, ETH Hoenggerberg, CH-8093 Zurich, Switzerland |
| Abstract: | This study reports on in vivo particle induced X-ray emission (PIXE) measurements combined with Rutherford backscattering spectroscopy (RBS) analyses of new remodeled sheep bone formed around TiAlV screws. The implants (screws) were anodized by a modified TiMax™ process. The interface between the implant and the bone was carefully investigated. [Zn]/[Ca] in-depth composition profiles as well as Ca, Fe elemental maps were recorded. The thickness of new bone formed around the screw reached 300-400 μm. Osteon and Osteoid phases were identified in the new bone. A higher [Zn]/[Ca] ratio was observed in the new bone as compared to the mature bone. Blood vessels were observed in the bone in close contact with the screw.This study shows the potential of ion beam analysis for biological and biomedical characterization. |
| Keywords: | 68.35.Bm 82.80.Yc 82.80.Ej 87.64.Kd 87.85.Jj 89.20.Bb |
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