Quantitative analysis of seizure frequency 1 week and 6, 12, and 24 months after surgery of epilepsy |
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Authors: | H Lüders D Murphy I Awad E Wyllie DS Dinner HH Morris AD Rothner |
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Affiliation: | Cleveland Clinic Epilepsy Program, Cleveland Clinic Foundation, OH 44195-5226. |
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Abstract: | We made quantitative analysis of seizure frequency 1 week and 6, 12, and 24 months after seizure surgery. Seizure recurrence was significantly higher when seizures occurred in the first postoperative week. Seizure recurrence increased progressively with longer follow-ups, but the 6 month postoperative follow-up period was an excellent index of long-term outcome. In operative follow-up studies, seizure frequency should be reported at fixed follow-up periods, e.g., at 6 months and 1, 2, 5, and 10 years. Meaningful comparison of outcomes between different studies is possible only when reports include outcome at fixed postoperative follow-up periods (as opposed to ranges of follow-up periods). |
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