Antithrombotic activity of fractions and components obtained from raspberry leaves (Rubus chingii) |
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Authors: | Na HanYuhong Gu Chun YeYan Cao Zhihui LiuJun Yin |
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Affiliation: | Department of Pharmacognosy, Shenyang Pharmaceutical University, 48#, Wenhua Road 103, Shenhe District, PR China |
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Abstract: | The 70% ethanol fraction from an aqueous extract of raspberry leaves was shown to be the most antithrombotic fraction in in vitro and in vivo tests. The total flavonoids and phenolics in this fraction were 0.286 g/g and 0.518 g/g by colorimetry. Six compounds, including salicylic acid, kaempferol, quercetin, tiliroside, quercetin 3-O-β-d-glucopyranoside and kaempferol 3-O-β-d-glucopyranoside, were isolated from the active fraction. Among them, kaempferol, quercetin and tiliroside obviously delayed plasma recalcification time (PRT) in blood. |
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Keywords: | Raspberry leaves Flavonoids Antithrombotic activity |
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