| 磁性分子印迹聚合物在天然活性物质分离纯化中的研究进展 |
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| 引用本文： | 王艳辉,郑光耀,闫林林. 磁性分子印迹聚合物在天然活性物质分离纯化中的研究进展[J]. 食品工业科技, 2023, 44(11): 442-450. DOI: 10.13386/j.issn1002-0306.2022070368 |
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| 作者姓名： | 王艳辉 郑光耀 闫林林 |
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| 作者单位： | 中国林业科学研究院 林产化学工业研究所；生物质化学利用国家工程实验室；国家林业和草原局林产化学工程重点实验室；江苏省生物质能源与材料重点实验室；江苏省林业资源高效加工利用协同创新中心，江苏南京 210042 |
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| 基金项目： | 国家自然科学基金（31901236）；北京工商大学北京市植物资源研究开发重点实验室开放课题基金（PRRD-2018-YB8）。 |
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| 摘 要： | 磁性分子印迹聚合物是将磁性纳米粒子与分子印迹聚合物组装而成的一类新型分离材料，具有选择性高、易分离和易再生的特点，可被用于食品、药品检测前处理以及天然活性物质的分离纯化等领域。本文介绍了磁性分子印迹技术的制备原理和方法，重点综述了近5年（2017～2022）磁性分子印迹聚合物在多酚类、生物碱、有机酸、萜类以及生物大分子化合物等天然活性物质的分离纯化方面的研究进展，并针对当前分离纯化领域的研究难点进行了讨论，以期为高值化、低含量的天然活性成分的富集、纯化及其分析检测提供研究参考。
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| 关 键 词： | 磁性 分子印迹聚合物 分离纯化 天然活性物质 |
| 收稿时间： | 2022-08-02 |
Research Progress of Magnetic Molecularly Imprinted Polymers in Separation and Purification of Natural Active Substances |
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| WANG Yanhui,ZHENG Guangyao,YAN Linlin. Research Progress of Magnetic Molecularly Imprinted Polymers in Separation and Purification of Natural Active Substances[J]. Science and Technology of Food Industry, 2023, 44(11): 442-450. DOI: 10.13386/j.issn1002-0306.2022070368 |
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| Authors: | WANG Yanhui ZHENG Guangyao YAN Linlin |
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| Affiliation: | Institute of Chemical Industry of Forest Products, CAF; National Engineering Lab. for Biomass Chemical Utilization; Key Lab. of Chemical Engineering of Forest Products, National Forestry and Grassland Administration; Key Lab. of Biomass Energy and Material, Jiangsu Province; Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, Nanjing 210042, China |
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| Abstract: | Magnetic molecularly imprinted polymers are novel separation materials assembled by magnetic nanoparticles and molecularly imprinted polymers, with specific selectivity, easy separation and regeneration, which can be used in the preliminary treatment of food and drugs, and the separation and purification of natural active substances. Herein, the preparation principle and method of magnetic molecular imprinting technology are elucidated, and the research progress (2017~2022) of magnetic molecular imprinting polymers in the separation and purification of natural active substances, such as polyphenols, alkaloids, organic acids, terpenoids, and macromolecules are reviewed. Meanwhile, the difficulties in the field of separation and purification are discussed. This review will provide reference for the enrichment, purification, analysis and detection of natural active substances. |
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