Viburnum mullaha D. DON fruit (Indian cranberry): A potential source of polyphenol with rich antioxidant,anti-elastase,anti-collagenase,and anti-tyrosinase activities |
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Authors: | Himani Singh Madhuri Kaushish Lily |
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Affiliation: | Department of Biotechnology, Modern Institute of Technology, Dhalwala, Rishikesh, Uttarakhand, India |
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Abstract: | Viburnum mullaha (Buch.-Ham. Ex D. Don), is an underexplored wild edible fruit of Indian Himalayan region, analyzed for total polyphenol contents, antioxidant, anti-elastase, anti-collagenase, and anti-tyrosinase activities using in vitro assays. High values of total phenolic contents of 1257 ± 40 mg gallic acid equivalents/100 g fruit weight and total flavonoid contents of 3501 ± 203 mg catechin equivalents/100 g fruit weight were observed. V. mullaha fruit extracts showed outstanding antioxidant activities (ABTS+, 1,1-diphenyl-2-picrylhydrazyl, superoxide anion, linoleate peroxyl radicals scavenging, and ferric reducing activities) and remarkable anti-elastase, anti-collagenase, and anti-tyrosinase activities. High resolution liquid chromatography–mass spectroscopy analysis revealed presence of 15 phenolic compounds, namely, chlorogenic acid, acetyl salicylic acid, dihydrorobinetin, dihydromyricetin, 2-isoprenylemodin, rutin, cosmosiin hexaacetate, pectolinarin, dihydroquercetin, eriodictyol, iriginol hexaacetate, theaflavin, epicatechin-pentaacetate, lomatin, and peucenin in fruit extracts. This study recommends utilization of V. mullaha fruit as functional food with prospective pharmaceutical, nutraceutical, and cosmeceutical properties. |
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Keywords: | Antioxidant Anti-elastase Anti-collagenase Anti-tyrosinase Polyphenols Wild-edible fruits of Himalaya |
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