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PARTICLE TRANSMISSION EFFICIENCY THROUGH THE NOZZLE OF THE API AEROSIZERTM
Affiliation:2. Institute of Environmental Engineering, National Chiao Tung University, No. 75 Poai St., Hsin Chu, Taiwan;3. Institute of Experimental Physics, University of Vienna, Boltzmanngasse 5, A-1090, Vienna, Austria;4. Center for Industrial Safety and Health Technology, Industrial Technology Research Institute, Hsin Chu, Taiwan;1. Department of Laboratory Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310000, China;2. Key Laboratory of Clinical In Vitro Diagnostic Techniques of Zhejiang Province, Hangzhou, 310000, China;3. Institute of Laboratory Medicine, Zhejiang University, Hangzhou, 310000, China;4. State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310000, China;5. Institute of Refrigeration and Cryogenics, Key Laboratory of Refrigeration and Cryogenic Technology of Zhejiang Province, Zhejiang University, Hangzhou, 310000, China;6. Department of Mechanical Engineering, The University of Hong Kong, Pokfulam, 999077 Hong Kong Special Administrative Region;7. School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 999077, Hong Kong Special Administrative Region;8. Department of Nosocomial Infection Control, College of Medicine, Zhejiang University, Hangzhou, 310000, China;1. Department of Environmental Science, Faculty of Environment, Kasetsart University, Bangkok, 10900, Thailand;2. Department of Environmental Technology and Management, Faculty of Environment, Kasetsart University, Bangkok, 10900, Thailand;3. Faculty of Physics, University of Vienna, Vienna, 1010, Austria;1. School of Perfume and Aroma Technology, Shanghai Institute of Technology, Shanghai, 200235, China;2. University Think Tank of Shanghai Municipality, Institute of Beautiful China and Ecological Civilization, Shanghai, 200235, China
Abstract:This study has investigated the particle transmission efficiency through the nozzle of the API AerosizerTM numerically. Two-dimensional flow field in the nozzle was first simulated. Particle trajectories for both liquid and solid particles were then calculated to obtain the particle transmission efficiency under various conditions. This study shows that particle aerodynamic diameter, particle materials, particle density and laser beam diameter influence the transmission efficiency. The transmission efficiency is found to increase with increasing particle diameter when the particle aerodynamic diameter is less than several micrometers. The efficiency for liquid particles drops significantly when particle aerodynamic diameter increases from several micrometers because of particle impaction loss in the nozzle. For solid particles, the relationship of the efficiency with particle diameter is found to be more complicated. For particles less than several micrometers in aerodynamic diameter, solid particles behave similarly to the liquid particles. However, as particles are greater than several micrometers, the effect of solid particle bounce is to increase the transmission efficiency with increasing aerodynamic diameter until particles become large enough so that plastic deformation occurs in the particles. Then the transmission efficiency will decrease with increasing particle aerodynamic diameter.
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