北方地区成人脂肪肝危险因素的病例对照研究

目的：探索北方地区成人脂肪肝的危险因素。方法：采用病例对照研究对294名病例和655名对照的相关资料进行非条件Logistic回归分析。结果：超重（OR=6．3，95％CI=4．4，8．9）、肥胖（OR=16．9，95％CI=9．9，28．9）、腹型肥胖（OR：2．9，95％CI=1．9，4．5）、血脂异常（OR=2．1，95％CI：1．5，3．0）及ST．T改变（OR=1．6，95％CI=1．0，2．3）与脂肪肝的患病明显相关（P〈0．05）。摄入肉类较多、高盐饮食及自觉压力较大均为脂肪肝的危险因素，其OR值分别为1．5（95％CI，1．0，2．1）、1．5（95％CI，1．1，2．1）及1．4（95％CI，1．0，2．2）。在家就餐超过5d为脂肪肝的保护因素，OR为0．6（95％CI，0．4，0．9）。结论：脂肪肝的发生与代谢性疾病及生活方式密切相关。

Case-control Study on the Risk Factors of Fatty Liver Disease in Northern People

Objective] To investigate the risk factors for fatty liver disease in northern people. Method] Data of case-control study including 294 cases and 655 controls were analyzed using non-conditional logistic regression. Result] Overweight （ OR =6. 3, 95% CI =4.4, 8.9）, obesity （ OR = 16. 9, 95% CI = 9.9, 28.9）, abdominal obesity （ OR = 2.9, 95% CI = 1.9, 4. 5 ）, dyslipidemia （ OR -- 2. 1, 95% CI = 1.5, 3.0 ） and ST-T changes （OR = 1.6, 95% CI = 1.0, 2. 3 ） were significantly associated with the risk of fatty liver disease （ P 〈 0. 05）. High intake of meat, high-salt diet and pressure were the risk factors of fatty liver disease, and the OR values were 1.5 （95% CI, 1.0, 2. 1 ）, 1.5 （95% CI, 1.1,2. 1 ） and 1.4 （95% CI, 1.0, 2. 2）, respectively. Eating at home more than 5 d was a protective factor for fatty liver and the OR value was 0. 6 （95% CI 0. 4, 0. 9） . Conclusion] The occurrence of fatty liver is closely associated with metabolic diseases and unhealthy lifestyle.