| 疫苗免疫毒理学评价的研究进展 |
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| 引用本文： | 董娜,徐苗,秦川,王国治.疫苗免疫毒理学评价的研究进展[J].粉末涂料与涂装,2010,23(2). |
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| 作者姓名： | 董娜 徐苗 秦川 王国治 |
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| 作者单位： | 董娜,秦川(中国医学科学院实验动物研究所北京协和医学院实验动物学部,北京,100021);徐苗,王国治(中国药品生物制品榆定所菌苗室,北京,100050) |
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| 摘 要： | 由于疫苗引起的不良反应多与免疫反应相关,因此免疫毒理学评价在疫苗的安全性评价中显得尤为重要。本文就疫苗免疫毒性包括超敏反应、免疫抑制和自身免疫反应的发生机理及其评价方法的研究进展作一综述。
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| 关 键 词： | 疫苗 免疫毒理学 不良反应 |
Progress in Research on Immunotoxicologic Evaluation of Vaccine |
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| DONG Na,XU Miao,QIN Chuan,et al.Progress in Research on Immunotoxicologic Evaluation of Vaccine[J].Chinese Journal of Biologicals,2010,23(2). |
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| Authors: | DONG Na XU Miao QIN Chuan |
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| Affiliation: | DONG Na,XU Miao,QIN Chuan,et al(Institute of Laboratory Animal Science,Chinese Academy of Medical Science , Peking Union Medical College,Beijing 100021,China) |
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| Abstract: | Most of the adverse reactions caused by vaccination are correlated with immune response,therefore it is very important to evaluate the immunotoxicity in safety evaluation of vaccine.This paper reviews the progress in research on mechanism and methods for immunotoxicologic evaluation of vaccine,including those of hypersensitivity,immune suppression and autoimmune response. |
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| Keywords: | Vaccine Immunotoxicology Adverse reaction |
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