| 抗肿瘤药物10-羟基喜树碱的研究与应用进展 |
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| 引用本文： | 袁丹,容如滨,喻宗沅,李忠铭. 抗肿瘤药物10-羟基喜树碱的研究与应用进展[J]. 化学与生物工程, 2007, 24(12): 9-11,24 |
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| 作者姓名： | 袁丹 容如滨 喻宗沅 李忠铭 |
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| 作者单位： | 湖北省化学研究院,湖北,武汉,430074;江汉大学化学与环境工程学院,湖北,武汉,430056 |
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| 摘 要： | 10-羟基喜树碱(HCPT)是一种重要的抗肿瘤药物,其制备和应用是有机化学和药物化学研究的热点.介绍了HCPT的主要特点、制备方法及其在治疗不同肿瘤中的作用.
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| 关 键 词： | 喜树碱 10-羟基喜树碱 制备 |
| 文章编号： | 1672-5425（2007）12-0009-03 |
| 收稿时间： | 2007-07-31 |
| 修稿时间： | 2007-07-31 |
The Progress of Research and Application of Anticancer Drug 10-Hydroxy Camptothecin |
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| YUAN Dan,RONG Ru-bing,YU Zong-yuan,LI Zhong-ming. The Progress of Research and Application of Anticancer Drug 10-Hydroxy Camptothecin[J]. Chemistry & Bioengineering, 2007, 24(12): 9-11,24 |
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| Authors: | YUAN Dan RONG Ru-bing YU Zong-yuan LI Zhong-ming |
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| Abstract: | chemistry an The preparation and application of d medical chemistry, as a crucial a 10-hydroxy camptothecin are hotspot in the field of organic nticancer drug. The major characterizations and preparation methods of 10-hydroxy camptothecin were introduced in the paper. The applications of 10-hydroxy camptothecin in therapy of various cancers were introduced too. |
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| Keywords: | camptothecin 10-hydroxy camptothecin preparation |
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