The response of adenoid cystic carcinoma to tamoxifen |
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Authors: | A Shadaba MN Gaze HR Grant |
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Affiliation: | Royal National Throat, Nose and Ear Hospital, London, UK. |
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Abstract: | Adenoid cystic carcinoma of the parotid gland often recurs locally, or metastases develop, after initial treatment with surgery and radiotherapy. We report a patient with an inoperable local recurrence of previously irradiated adenoid cystic carcinoma, who was treated with tamoxifen, an oestrogen receptor antagonist. After 18 months of treatment with tamoxifen, MRI showed a partial response, and further clinical progression of the disease was halted. |
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