环糊精催化有机反应的进展

环糊精通过主客体相互作用能将疏水性有机分子转移到对环境友好的水中进行有机反应,还能影响分子的电性环境,使反应在温和的条件下就能获得良好的收率,几乎没有副产物,在有机合成中应用十分广泛。本文就近年来环糊精在有机合成中的催化应用分为氧化、加成、开环、水解、偶联和取代等几种反应类型,并对这些反应进行了概述。

Progress in organic reaction catalyzed by cyclodextrins

Cyclodextrins,widely applied in organic synthesis,can transfer hydrophobic molecules into water by the supramolecular interaction.As an important kind of host molecules,they can also influence the microenvironment of hydrophobic molecules by the host-guest interaction and change traditional reaction conditions to obtain good yield without by product.The recent developments of catalyzed application of cyclodextrins in organic reactions such as oxidation reaction,addition reaction,ring opening reaction,hydrolysis reaction,coupling reaction,substitution reaction,etc.are reviewed.The catalytic mechanisms are also discussed in this article.