| 肿瘤受体显像剂99Tcm-octreotide的放化纯度分析 |
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| 引用本文： | 王叙馥,左书耀,邵文博,王国明,孙建文,张勤.肿瘤受体显像剂99Tcm-octreotide的放化纯度分析[J].同位素,2003,16(1):26-29. |
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| 作者姓名： | 王叙馥 左书耀 邵文博 王国明 孙建文 张勤 |
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| 作者单位： | 青岛大学医学院附属医院核医学科,山东,青岛,266003 |
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| 摘 要： | 采用高压液相色谱分析(HPLC)和双层析结合银染色两种方法，对新型肿瘤受体显像剂^99Tc^m—oc—treotide的放化纯度进行分析。结果表明，双层析法结合银染色可以准确、有效地分离^99Tc^m—octreotide及其它放射性组分，可以较精确地计算出显像剂的放化纯度。为Octreotide及其它多肤类显像剂的放化纯度测定提供了一种简捷、准确的新手段。
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| 关 键 词： | 肿瘤受体显像剂 放化纯度分析 高压液相色谱分析 银染色 双层析 奥曲肽 肿瘤定位 |
| 文章编号： | 1000-7512(2003)01-0026-04 |
| 修稿时间： | 2002年7月29日 |
The Analytical of Radiochemical Purity of Tumor Receptor Imaging Agent 99Tcm-octreotide |
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| WANG Xu-fu,ZUO Shu-yao,SHAO Wen-bo,WANG Guo-ming,SUN Jian-wen,ZHANG Qin.The Analytical of Radiochemical Purity of Tumor Receptor Imaging Agent 99Tcm-octreotide[J].Isotopes,2003,16(1):26-29. |
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| Authors: | WANG Xu-fu ZUO Shu-yao SHAO Wen-bo WANG Guo-ming SUN Jian-wen ZHANG Qin |
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| Abstract: | The radiochemical purity of tumor receptor imaging agent 99Tcm-octreotide is measured by High Pressure Liquid Chromatography (HPLC) and two systems of chromatography combining method of silver stain. The results show that the radiochemical purity of 99Tcm-octreotide measured by both methods are effective and correct. It can separate 99Tcm-octreotide from other radioactive compositions correctly and effectively. |
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| Keywords: | 99Tcm-octreotide radiochemical purity two systems of chromatography silver stain high pressure liquid chromatography |
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