The values of selected lipid parameters and atrial pressure in persons with hyperinsulinemia and normal glucose tolerance

In 60 healthy non-obese persons we determined fasting plasma insulin concentrations. Afterwards we performed test with oral load with 75 g glucose. We determined plasma concentration of insulin one hour and two hours after this load; we found that 14 of 60 subjects had hyperinsulinemia with normal glucose tolerance. In the group of persons with hyperinsulinaemia we have shown the increase of fasting plasma triglyceride levels and elevated diastolic blood pressure. We suggested that healthy persons with hyperinsulinemia and normal glucose tolerance have an increase risk for cardiovascular diseases.