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Comparison of two models for the estimation of usual intake addressing zero consumption and non-normality
Authors:Waldo J de Boer  Hilko van der Voet  Bas GH Bokkers  Martine I Bakker  Polly E Boon
Affiliation:1. Biometris, Wageningen University and Research Centre , Wageningen, The Netherlands;2. RIKILT, Institute of Food Safety, Wageningen University and Research Centre , Wageningen, The Netherlands waldo.deboer@wur.nl;4. RIKILT, Institute of Food Safety, Wageningen University and Research Centre , Wageningen, The Netherlands;5. RIVM, National Institute for Public Health and the Environment , Bilthoven, The Netherlands;6. RIKILT, Institute of Food Safety, Wageningen University and Research Centre , Wageningen, The Netherlands
Abstract:Various models exist for estimating the usual intake distribution from dietary intake data. In this paper, we compare two of these models, the Iowa State University Foods (ISUF) model and the betabinomial-normal (BBN) model and apply them to three different datasets. Intake data are obtained by aggregating over multiple food products and are often non-normal. The ISUF and BBN model both address non-normality. While the two models have similar structures, they show some differences. The ISUF model includes an additional spline transformation for improving the normality of the intake amount distribution, while the BBN model includes the possibility of addressing covariates, such as age or sex. Our analyses showed that for two of the example datasets both models produced similar estimates of the higher percentiles of the usual intake distribution. However, for the third dataset, where the intake amount distribution appear to be multimodal, both models produced different percentile estimates.
Keywords:exposure  probabilistic modeling  risk assessment  modeling  statistical analysis  Acrylamide  mycotoxins  other natural toxicants  alkaloids  fruit  potatoes  processed foods
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