农药中间体2—氯—5—氨甲基吡啶的合成研究

农药重要中间体２－氯－５－氨甲基吡啶是由Ｎ－（２－氯代吡啶－５－甲基）－邻苯二甲酰亚胺先在碱水溶液中水解，再在稀酸中水解而制得的高收率产品，讨论了反应条件对合成反应的影响。产品总收率为８２％以上。

Study on Synthesis of Pesticide Intermediate 2- Chloro -5 - aminomethylpyridine

2-Chloro- 5 - aminomethylpyridine, useful as an intermediates for agrochemicals, was prepared in high yield from N - (2 - chloropyridine- 5- methyl) - phthalimide, which was hydrolyzed first in aqueous alkaline solution, and then in dilute aqueous mineral acid solution, and a high yield of the title product could be achieved.The reaction conditions have been discussed,and the total yield has been above 82%.