Granulocyte and granulocyte-macrophage colony-stimulating factors, their receptors and interleukin-3 levels in newborns |
| |
Authors: | M Co?kun F Kardelen N Oygür L Undar A Sava? O Ye?in |
| |
Affiliation: | Servicio de Endocrinología, Hospital Infantil La Paz, Madrid. |
| |
Abstract: | OBJECTIVE: The objective of this study was to determine the incidence of macrosomia in infants of diabetic mothers (IDM) and to analyze its possible correlation with insulin, C-peptide, growth hormone (GH) and IGF-I levels in umbilical cord blood. PATIENTS AND METHODS: A prospective study of 58 IDM and 58 control newborns (33 males and 25 females in both groups) was carried out. RESULTS: The incidence of macrosomia was 25.8% in the IDM group and 61.5% in the IIDDM group (infant of insulin-dependent diabetic mother) compared to 5% in the control group. There was a positive correlation between maternal Hgb Alc levels in the third trimester of gestation and insulin and C-peptide levels with newborn weight in the IDM group (especially in the IIDDM group). IGF-I levels were positively correlated with newborn weight in both control and IDM groups. There was no correlation between GH and IGF-I levels in any group. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|