益生菌对生物体内持久性有机污染物和重金属的调节作用研究进展

持久性有机污染物和重金属的污染问题是全球关注的重要问题,其持续暴露会带来严重的生态风险和健康问题。这些污染物具有稳定的物理和化学性质,在生物体和环境中存在持久性、生物累积性、毒性以及较强的长距离迁移的能力而受到广泛关注。研究表明,持久性有机污染物和重金属在生物体内的积累会引起生物体的氧化应激和免疫损伤,破坏肠道微生物群的组成结构,打破肠道菌群的平衡。益生菌能够维持宿主肠道微生物群的平衡与稳定,有效提高生物体的抗氧化能力和免疫细胞的活性。益生菌已被证明能够减少宿主体内污染物的积累、提高宿主的免疫功能和调节肠道菌群的平衡,从而降低污染物引起的毒性作用。因此,本文综述了益生菌对生物体内持久性污染物和重金属毒性的调节作用,旨在为污染物的消减提供理论参考。

Research progress on the regulatory effects of probiotics on persistent organic pollutants and heavy metals in organisms

Contamination of persistent organic pollutants and heavy metals is an important issue of global concern, and their continued exposure poses serious ecological risks and health problems. These pollutants are of widespread conern because of their stable physical and chemical properties, persistence in organisms and the environment, bioaccumulation, toxicity and high capacity for long-rang transport. Previous studies have shown that the accumulation of persistent organic pollutants and heavy metals in organisms can cause oxidative stress and immune damage, disrupt the composition and upset the balance of the intestinal microbiota.. Probiotics can maintain the balance and stability of the host''s intestinal microbiota and effectively improve the organism''s antioxidant capacity and immune cell activity. And probiotics have been shown to reduce the accumulation of pollutants in the host, improve the host''s immune function and regulate the balance of intestinal microbiota, thus reducing the toxic effects caused by pollutants. Therefore, this paper reviewed the role of probiotics in regulating the toxicity of persistent pollutants and heavy metals in organisms,, aiming to provide theoretical references for the abatement of pollutants.