Synthese von 2-[Benzazolyl-(2)]-3,3-bis-(alkylthio)-acrylnitrilen und Umsetzungen mit N-Nucleophilen

Synthesis of 2-Benzazolyl-(2)]-3,3-bis-(alkylthio)-acrylnitriles and Their Reactions with N-Nucleophiles The reactions of benzazolyl-(2)-acetonitriles 1 (1H-benzimidazolyl-, 1-methylbenzimidazolyl-, benzoxazolyl- and benzothiazolyl-) with carbon disulfide in the presence of sodium hydride in dimethylsulfoxide and methylation yield the 2-benzazolyl-(2)]-3,3-bis-(alkylthio)-acrylonitriles 3 – 5 reacting with amines to the keten-S,N-acetals 6 – 9 . If dinucleophilic reagents are used heterocyclic systems 10 – 14 are formed.