| 烷基化果胶的合成工艺 |
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| 引用本文： | 郑学芳,杨华,刘力恒,韦金. 烷基化果胶的合成工艺[J]. 化学世界, 2008, 49(7) |
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| 作者姓名： | 郑学芳 杨华 刘力恒 韦金 |
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| 作者单位： | 广西大学化学化工学院,广西,南宁,530004;广西大学化学化工学院,广西,南宁,530004;广西大学化学化工学院,广西,南宁,530004;广西大学化学化工学院,广西,南宁,530004 |
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| 摘 要： | 为了得到新的结肠靶向给药载体,制备了烷基化甲胶(Alkyl-pectin)。方法:在碱性条件下,以四丁基溴化铵为催化剂,用溴代正辛烷对果胶进行化学改性。结果表明:改性后的果胶是疏水的,并用红外光谱、元素分析、差示扫描量热、核磁共振等方法对产品进行了表征。
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| 关 键 词： | 烷基化果胶 溴辛烷 四丁基溴化铵 疏水性 |
Study on the Synthesis of Alkyl-pectin |
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| ZHENG Xue-fang,YANG Hua,LIU Li-heng,WEI Jin. Study on the Synthesis of Alkyl-pectin[J]. Chemical World, 2008, 49(7) |
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| Authors: | ZHENG Xue-fang YANG Hua LIU Li-heng WEI Jin |
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| Abstract: | In order to obtain a new carrier for the colon-specific drug,alkyl-pectin was prepared.The modification of pectin with 1-bromoctane in the presence of an alkali was studied using tetrabutyl ammonium bromide as catalyst.The result showed that the alkyl-pectin abtained was water resistant.The alkyl-pectin structure was characterized by FT IR、EA、DSC and ~1H NMR analysis. |
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| Keywords: | alkyl-pectin 1-bromoctane tetrabutyl ammonium bromide hydrophobicity |
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